Developing First-in-Class
Cell Therapies
(Counter Regulatory T-cells)

Pioneering Treg Therapies for Autoimmune Diseases

Developing novel, First-in-Class CD6/CTLA-4 CAR-Tregs for Type 1 Diabetes, Dermatological, and Neuroinflammatory Autoimmune Diseases.

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What are Counter Regulatory T-cells

Immuthera is developing CD6/CTLA4 CoRe-T cells that act in the body to counter imbalances in the immune system by directly targeting and suppressing the autoreactive T-cells that do all of the damage autoimmune disorders. Immuthera will build upon the CoRe-T platform via collaboration with partners to develop other T-regulatory cell therapies including next generation CAR-Tregs and In-Vivo Generated Antigen Specific Tregs utilizing advanced mRNA/LNP technologies.

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OUR SCIENCE

Treg Cell Technology

Maintaining Balance

T regulatory cells (Tregs) play a critical role in maintaining immune homeostasis. Immuthera’s CoRe-T cells are CAR-Tregs that control and suppress harmful immune reactions in autoimmune diseases by directly targeting destructive and autoreactive T-cells wherever they are located.

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Type 1 diabetes

Presymptomatic (stage 1)

PTG-007+ / rituximab

Dermatological Autoimmune

Neuroinflammatory Autoimmune

Rheumatoid Arthritis

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01

City of Hope aims to make hope a reality for all touched by cancer and diabetes. Founded in 1913, City of Hope has grown into one of the largest and most advanced cancer research and treatment organizations in the United States, and one of the leading research centers for diabetes and other life-threatening illnesses.
02

PolTREG S.A. is the most clinically advanced company developing Tregulatory cell therapies for Autoimmune and Neuroinflammatory diseases.
03

Antion Biosciences SA is a cell and gene engineering biotechnology company based in Geneva (Switzerland), developing off-the-shelf therapies for the treatment of diseases with significant unmet medical needs.
04

Kinexum is an international healthcare consulting group specializing in regulatory strategy, clinical development, and commercialization.
05

McDermott Will & Emery is an industry leading lawfirm that partners with leaders around the world to fuel missions, knock down barriers and shape markets.